Computer recreation of a pepsin.
The enzyme pepsin in its typical position in the stomach.
  • Pepsin is an enzyme produced in the stomach in response to protein intake in food. Specifically, it's a proteolytic enzyme. This means that it's capable of digesting other proteins.
  • Technically, you don't necessarily need pepsin to digest the protein that you eat. Since proteins are made of amino acids, the peptide bonds between these units are dissolved by your gastric acids.
  • Pepsin is made with the purpose of breaking down its substrate, protein. After the chemical reaction occurs between the pepsin and the protein, the product peptide is created.
  • Typically, the optimum pH is 1.5 to 2.0, and the optimum temperature is between 30° and 40° C.

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