gigantism

is a condition characterized by excessive growth and height significantly above average. In humans, this condition is caused by over-production of growth hormone in childhood resulting in persons between 2.13 m (7 feet or 84 inches) and 2.74 m (9 feet or 108 inches) in height.

Gigantism is usually caused by a tumor on the pituitary gland of the brain. It causes growth of the hands, face, and feet. In some cases the condition can be passed on genetically through a mutated gene.

In the past, while many of them were social outcasts because of their height, some (usually unintentionally) found employment in Friedrich Wilhelm I's famous Potsdam Giants regiment.

Many of those who have been identified with gigantism have suffered from multiple health issues involving their circulatory or skeletal system.

The child will grow in height, as well as in the muscles and organs. This excessive growth makes the child extremely large for his or her age.

CT or MRI scan of the head showing pituitary tumor

  • Failure to suppress serum growth hormone (GH) levels after an oral glucose challenge (maximum 75g)
  • High prolactin levels
  • Increased insulin growth factor-I (IGF-I) levels
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