I believe that one aspect of Mesopotamia that makes their civilization advanced is their system of writing. Their system of writing was the first known to man kind.they used it for different needs, but mainly for recording history. They use symbols to represent things or numbers.
Their art was also advanced, they used different utensils for creating art. For example: the cylinder seals were made from a cylinder made of clay, pressed and rolled against carvings.
Their materials were advanced by the way they're made. They were made by different tools and the people. For example: weapons were stronger by being made out of gold and silver instead of clay and wood.