The substrate of a Nuclease is a nucleic acid i.e. DNA or RNA.
The product name of a Nuclease is polynucleotidase.
The Nuclease is from Nucleic acids and helps break them down.
The break down basically takes apart Nucleic acids and making them easier to digest. This is what metabolism is, which makes us maintain a easy digestive system.
Optimal ph for nuclease is 9.2 and optimal temp. is 37 degrees.
http://www.sciencedirect.com/science/article/pii/0... ph level and temp
http://en.wikipedia.org/wiki/Nuclease Substrate, product, and reaction
http://www.genetik.uni-koeln.de/groups/Kemper/nucl... where it comes from