PSEUDOBULBAR AFFECT

Psuedobulbar affect (PBA) is a condition caused by injuries or damage to parts of the brain that control emotions. This causes sudden laughing or crying. an episode of PBA can happen at any time, can't be controlled, and it isn't triggered by anything. Pseudobulbar affect is a disinhibition syndrome in which pathways involving serotonin and glutimate are disrupted. PBA is often associated with other neurological disorders or nervous system disorders such as amytrophic lateral sclerosis (ALS), multiple sclerosis (MS), extrapyramidal and cerebellar disorders, traumatic brain injury (TBI) , Alzheimer's disease, brain tumors, and/or dementia. It is commonly misidentified as a mood disorder,  particularly depression or a bipolar disorder. You would go to a neurologist to find out if you have PBA or not. A safe and effective treatment for PBA is a combination of dextromethorphan and quinidine.

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