One famous Byzantine emperor was Justinian I.Justinian ruled from AD 527 to 565.
- 521 AD Justinian is made Consul by his uncle Emperor Justin I.
- 525 AD Justinian I marries Theodora, a woman from a poor background and possibly a courtesan.
- 527 AD - 565 AD Reign of Byzantine Emperor Justinian I.
- 532 AD The Nika riots last a week in Constantinople during the reign of Justinian I. The disturbance caused the destruction of much of the central city area and was quelled after a significant loss of life.
- 533 AD - 534 AD The Vandal War launched by Emperor Justinian I, aimed a reconquering Africa from the Vandals.
- 534 CEJustinian of the Byzantine Empire conquers the Vandal kingdom in Africa.
- 535 CE - 554 AD The Gothic War launched by Emperor Justinian I, aimed at reconquering Italy from the Goths.
- Jul 556 AD - c. Jul 572 CESamaritan revolt beginning in Caesarea Maritima, perhaps with Jewish support. A number of churches are destroyed and there is a significant loss of life.
- 565 AD Death of Justinian I after 38 years ruling the Roman Empire.